Micky van de Ven Double Halts Everton's Unbeaten Streak at Brand New Stadium
The Dutch defender emerged as the first defender to score twice in a Premier League match for Spurs since Jan Vertonghen in March 2013.
At a glance
The Spurs defender heads home two times in first half
Everton's Jake O'Brien has equalizer disallowed after video check
Senegalese midfielder scores third in dying moments
This loss is Everton's initial at Hill Dickinson Stadium
The Tottenham defender scored twice as Spurs extended their unbeaten run in away games in the top division and delivered Everton their first defeat at their new home.
The Toffees were unbeaten in their five previous fixtures at their new ground at Bramley-Moore Dock, having left Goodison Park behind after more than a century at the end of last season.
But Spurs captain Van de Ven struck twice from corners in the opening 45 minutes to place their strong form at jeopardy, and they were failed to turn it around before the midfielder - assisted by former Toffees attacker the Brazilian - headed home a third to seal the victory.
Jake O'Brien thought he had levelled the scores five minutes after Van de Ven's first goal, glancing a bullet header past Guglielmo Vicario from an set-piece.
Beto, meanwhile, failed to convert a number of opportunities, while Vicario made a series of fine saves to guarantee the London club went five away games unbeaten in the Premier League.
But the VAR stepped in, advising Craig Pawson to review the score on the pitchside monitor and the referee decided that the winger and Iliman Ndiaye were in offside positions and had impeded with the Tottenham goalkeeper.
The win elevates Thomas Frank's side up to third in the division, five points off local foes and leaders the Gunners.
Everton stay 14th and sit six points clear of the drop zone.
Tottenham analysis: The defender fulfils role at both ends of the field
Following a drab midweek display in the Champions League against Monaco, where they mustered a only attempts on target, Frank chose the French striker in attack instead of ex-Everton forward the Brazilian.
The summer signing was unable to make much of an impact before being replaced for Richarlison after an hour on the field, but it turns out he wasn't needed in the end.
Defender the Dutchman converted into an offensive threat to be reckoned with.
Spurs' opening strike came from a well-worked corner routine, with Rodrigo Bentancur directing the ball toward the six-yard box for an unmarked Van de Ven to score.
And Ven de Ven - filling in as captain in Cristian Romero's absence - added his next goal in first-half stoppage time as he rose above Jordan Pickford to nod in.
The Dutchman was equally impressive in defence, combining effectively with his defensive colleague as the pair handled excellently with the 34 crosses thrown their way by the opposition.
Toffees breakdown: Toffees missing finishing touch
Everton's recent stadium had been a happy hunting ground, but it appears the freshness may have faded slightly and supporters flocked to the exits after Sarr's third for Spurs.
The break in the team's unbeaten home run will not be a major concern for the manager, but their striker situation will be.
Beto and the other striker - the Toffees' pair of established centre-forwards - had netted just a single goal between them before Sunday's outing.
And they were failed to add to that miserable tally on a damp and dreary evening on in Liverpool.
The striker's form was summed up when he opted to overhead kick a golden opportunity from close range, even with having space and time to readjust for a more conventional shot that would have challenged the keeper.
The substitute, too, failed to influence the game after coming on for the starter in the 65th minute.
It wasn't for a shortage of chance. The majority of the home side's offensive moves came through Grealish and Ndiaye, who tirelessly delivered threatening balls into the Spurs penalty area.
Upcoming fixtures for both teams?
The Toffees: Moyes' men head to the Stadium of Light in the top flight on early November at 8 PM.
Tottenham: The London club travel to St James' Park on Wednesday, 29 October for their fourth-round League Cup match against Newcastle.